/ en /news/calico-and-broad-institute-extend-collaboration-adding-focus-age-related-neurodegeneration <span class="field field--name-title field--type-string field--label-hidden"><h1>Calico and ӳ����ý extend collaboration, adding focus on age-related neurodegeneration</h1> </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Corie Lok</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-05-09T08:30:10-04:00" class="datetime">May 9, 2024</time> </span> <div class="hero-section container"> <div class="hero-section__row row"> <div class="hero-section__content hero-section__content_left col-6"> <div class="hero-section__breadcrumbs"> <div class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/news">News</a> </li> </ol> </nav> </div> </div> <div class="hero-section__title"> <div class="block block-layout-builder block-field-blocknodelong-storytitle"> <span class="field field--name-title field--type-string field--label-hidden"><h1>Calico and ӳ����ý extend collaboration, adding focus on age-related neurodegeneration</h1> </span> </div> </div> <div class="hero-section__description"> <div class="block block-layout-builder block-field-blocknodelong-storybody"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The renewed agreement will continue to support ongoing programs focused on the biology and genetics of aging as well as early-stage drug discovery.</p> </div> </div> </div> <div class="hero-section__author"> <div class="block block-layout-builder block-extra-field-blocknodelong-storyextra-field-author-custom"> By Calico and ӳ����ý Communications </div> </div> <div class="hero-section__date"> <div class="block block-layout-builder block-field-blocknodelong-storycreated"> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-05-09T08:30:10-04:00" title="Thursday, May 9, 2024 - 08:30" class="datetime">May 9, 2024</time> </span> </div> </div> </div> <div class="hero-section__right col-6"> <div class="hero-section__image"> <div class="block block-layout-builder block-field-blocknodelong-storyfield-image"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"> <article class="media media--type-image media--view-mode-multiple-content-types-header"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <picture> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/DSC_6124-HDR.jpg?itok=WWY-t6G_ 1x" media="all and (min-width: 1921px)" type="image/jpeg" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/DSC_6124-HDR.jpg?itok=WWY-t6G_ 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/jpeg" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop/public/longstory/DSC_6124-HDR.jpg?itok=8c3DPXxW 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/jpeg" width="736" height="520"> <source srcset="/files/styles/multiple_ct_header_laptop/public/longstory/DSC_6124-HDR.jpg?itok=xug-Fei7 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/jpeg" width="641" height="451"> <source srcset="/files/styles/multiple_ct_header_tablet/public/longstory/DSC_6124-HDR.jpg?itok=9fuZYPQ7 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="706" height="417"> <source srcset="/files/styles/multiple_ct_header_phone/public/longstory/DSC_6124-HDR.jpg?itok=xAevPb6k 1x" media="all and (max-width: 539px)" 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field--label-hidden field__item"><p>Related news</p> </div> <div class="field field--name-field-content-reference field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><article about="/news/cancer-immunotherapy-candidate-provokes-powerful-dual-response-cancer-and-immune-cells" class="node"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"><article class="media media--type-image media--view-mode-multiple-ct-sidebar-link-with-image"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <a href="/news/cancer-immunotherapy-candidate-provokes-powerful-dual-response-cancer-and-immune-cells"><picture> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/longstory/p2_main_0.png?itok=LmB4RTrP 1x" media="all and (min-width: 1921px)" type="image/png" width="104" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop_xl/public/longstory/p2_main_0.png?itok=LmB4RTrP 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/png" width="104" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop/public/longstory/p2_main_0.png?itok=Y9KtLDw5 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/png" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_desktop/public/longstory/p2_main_0.png?itok=Y9KtLDw5 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/png" width="87" height="104"> <source srcset="/files/styles/multiple_ct_sidebar_link_with_image_tablet/public/longstory/p2_main_0.png?itok=bIRHRUgu 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/png" width="285" height="186"> <source 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about="/news/broad-institute-and-calico-announce-extensive-collaboration-focused-biology-aging-and" class="node"> <div class="node__content"> <a href="/news/broad-institute-and-calico-announce-extensive-collaboration-focused-biology-aging-and" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">ӳ����ý and Calico announce an extensive collaboration focused on the biology of aging and therapeutic approaches to diseases of aging</span> </a> </div> </article> </div> </div> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>Calico Life Sciences LLC (Calico) and the ӳ����ý of MIT and Harvard announced today that the two organizations have further extended their partnership with an added focus on age-related neurodegeneration. Initially announced in March 2015, this renewed agreement extends the collaboration until September 2029 and will continue to support ongoing programs focused on the biology and genetics of aging as well as early-stage drug discovery. Terms of the agreement were not disclosed.</p> <p>“We are pleased to continue our collaboration with the ӳ����ý. It is entering its tenth year and we’ve made a considerable amount of progress, including discoveries that could make immunotherapies more effective for more patients. We are currently testing this approach in two early-stage clinical trials evaluating a pair of PTPN2 inhibitors,” said Arthur Levinson, founder and CEO of Calico. “With the expansion of our partnership to include age-related neurodegeneration, we are tackling a critical area of discovery that will allow us to access our collective expertise to advance an important area of research and clinical development.”</p> <p>“Renewing our commitment to this partnership with Calico reflects our shared goal of advancing transformative biomedical research and therapies for age-related diseases,” said Todd Golub, director and founding core member of the ӳ����ý. “Since we initiated our partnership, we have seen tremendous advances across new technologies and analytic methods that are enabling the discovery of new biological insights into human disease that have immediate impact on drug discovery. We look forward to working with the Calico team to further our insights into how aging impacts the brain and neurological function.”</p> </div> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block-node-broad-tags block block-layout-builder block-field-blocknodelong-storyfield-broad-tags"> <div class="block-node-broad-tags__row"> <div class="block-node-broad-tags__title">Tags:</div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/broad-tags/aging" hreflang="en">Aging</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/neurodegeneration" hreflang="en">Neurodegeneration</a></div> </div> </div> </div> </div> </div> Thu, 09 May 2024 12:30:10 +0000 Corie Lok 5556886 at /news/schizophrenia-and-aging-may-share-common-biological-basis <span class="field field--name-title field--type-string field--label-hidden"><h1>Calico and ӳ����ý extend collaboration, adding focus on age-related neurodegeneration</h1> </span> <span class="field field--name-uid field--type-entity-reference field--label-hidden"> <span>By Corie Lok</span> </span> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-05-09T08:30:10-04:00" class="datetime">May 9, 2024</time> </span> <div class="hero-section container"> <div class="hero-section__row row"> <div class="hero-section__content hero-section__content_left col-6"> <div class="hero-section__breadcrumbs"> <div class="block block-system block-system-breadcrumb-block"> <nav class="breadcrumb" role="navigation" aria-labelledby="system-breadcrumb"> <h2 id="system-breadcrumb" class="visually-hidden">Breadcrumb</h2> <ol> <li> <a href="/">Home</a> </li> <li> <a href="/news">News</a> </li> </ol> </nav> </div> </div> <div class="hero-section__title"> <div class="block block-layout-builder block-field-blocknodelong-storytitle"> <span class="field field--name-title field--type-string field--label-hidden"><h1>Calico and ӳ����ý extend collaboration, adding focus on age-related neurodegeneration</h1> </span> </div> </div> <div class="hero-section__description"> <div class="block block-layout-builder block-field-blocknodelong-storybody"> <div class="clearfix text-formatted field field--name-body field--type-text-with-summary field--label-hidden field__item"><p>The renewed agreement will continue to support ongoing programs focused on the biology and genetics of aging as well as early-stage drug discovery.</p> </div> </div> </div> <div class="hero-section__author"> <div class="block block-layout-builder block-extra-field-blocknodelong-storyextra-field-author-custom"> By Calico and ӳ����ý Communications </div> </div> <div class="hero-section__date"> <div class="block block-layout-builder block-field-blocknodelong-storycreated"> <span class="field field--name-created field--type-created field--label-hidden"><time datetime="2024-05-09T08:30:10-04:00" title="Thursday, May 9, 2024 - 08:30" class="datetime">May 9, 2024</time> </span> </div> </div> </div> <div class="hero-section__right col-6"> <div class="hero-section__image"> <div class="block block-layout-builder block-field-blocknodelong-storyfield-image"> <div class="field field--name-field-image field--type-entity-reference field--label-hidden field__item"> <article class="media media--type-image media--view-mode-multiple-content-types-header"> <div class="field field--name-field-media-image field--type-image field--label-hidden field__item"> <picture> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/DSC_6124-HDR.jpg?itok=WWY-t6G_ 1x" media="all and (min-width: 1921px)" type="image/jpeg" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop_xl/public/longstory/DSC_6124-HDR.jpg?itok=WWY-t6G_ 1x" media="all and (min-width: 1601px) and (max-width: 1920px)" type="image/jpeg" width="754" height="503"> <source srcset="/files/styles/multiple_ct_header_desktop/public/longstory/DSC_6124-HDR.jpg?itok=8c3DPXxW 1x" media="all and (min-width: 1340px) and (max-width: 1600px)" type="image/jpeg" width="736" height="520"> <source srcset="/files/styles/multiple_ct_header_laptop/public/longstory/DSC_6124-HDR.jpg?itok=xug-Fei7 1x" media="all and (min-width: 800px) and (max-width: 1339px)" type="image/jpeg" width="641" height="451"> <source srcset="/files/styles/multiple_ct_header_tablet/public/longstory/DSC_6124-HDR.jpg?itok=9fuZYPQ7 1x" media="all and (min-width: 540px) and (max-width: 799px)" type="image/jpeg" width="706" height="417"> <source srcset="/files/styles/multiple_ct_header_phone/public/longstory/DSC_6124-HDR.jpg?itok=xAevPb6k 1x" media="all and (max-width: 539px)" type="image/jpeg" width="499" height="294"> <img loading="eager" width="499" height="294" src="/files/styles/multiple_ct_header_phone/public/longstory/DSC_6124-HDR.jpg?itok=xAevPb6k" alt="The outside of the ӳ����ý building at 415 Main St in Cambridge showing the ӳ����ý sign" title="The outside of the ӳ����ý building at 415 Main St in Cambridge showing the ӳ����ý sign" typeof="foaf:Image"> </picture> </div> <div class="media-caption"> <div class="media-caption__credit"> Credit: Ben Gibbs for The Eli and Edythe ӳ����ý Foundation </div> <div class="media-caption__description"> </div> </div> </article> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block block-better-social-sharing-buttons block-social-sharing-buttons-block"> <div style="display: none"><link rel="preload" href="/modules/contrib/better_social_sharing_buttons/assets/dist/sprites/social-icons--no-color.svg" as="image" type="image/svg+xml" 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about="/news/broad-institute-and-calico-announce-extensive-collaboration-focused-biology-aging-and" class="node"> <div class="node__content"> <a href="/news/broad-institute-and-calico-announce-extensive-collaboration-focused-biology-aging-and" class="node__title"><span class="field field--name-title field--type-string field--label-hidden">ӳ����ý and Calico announce an extensive collaboration focused on the biology of aging and therapeutic approaches to diseases of aging</span> </a> </div> </article> </div> </div> </div> </div> </div> </div> <div class="clearfix text-formatted field field--name-field-text field--type-text-long field--label-hidden field__item"><p>Calico Life Sciences LLC (Calico) and the ӳ����ý of MIT and Harvard announced today that the two organizations have further extended their partnership with an added focus on age-related neurodegeneration. Initially announced in March 2015, this renewed agreement extends the collaboration until September 2029 and will continue to support ongoing programs focused on the biology and genetics of aging as well as early-stage drug discovery. Terms of the agreement were not disclosed.</p> <p>“We are pleased to continue our collaboration with the ӳ����ý. It is entering its tenth year and we’ve made a considerable amount of progress, including discoveries that could make immunotherapies more effective for more patients. We are currently testing this approach in two early-stage clinical trials evaluating a pair of PTPN2 inhibitors,” said Arthur Levinson, founder and CEO of Calico. “With the expansion of our partnership to include age-related neurodegeneration, we are tackling a critical area of discovery that will allow us to access our collective expertise to advance an important area of research and clinical development.”</p> <p>“Renewing our commitment to this partnership with Calico reflects our shared goal of advancing transformative biomedical research and therapies for age-related diseases,” said Todd Golub, director and founding core member of the ӳ����ý. “Since we initiated our partnership, we have seen tremendous advances across new technologies and analytic methods that are enabling the discovery of new biological insights into human disease that have immediate impact on drug discovery. We look forward to working with the Calico team to further our insights into how aging impacts the brain and neurological function.”</p> </div> </div> </div> </div> </div> </div> </div> <div class="content-section container"> <div class="content-section__main"> <div class="block-node-broad-tags block block-layout-builder block-field-blocknodelong-storyfield-broad-tags"> <div class="block-node-broad-tags__row"> <div class="block-node-broad-tags__title">Tags:</div> <div class="field field--name-field-broad-tags field--type-entity-reference field--label-hidden field__items"> <div class="field__item"><a href="/broad-tags/aging" hreflang="en">Aging</a></div> <div class="field__item"><a href="/broad-tags/cancer" hreflang="en">Cancer</a></div> <div class="field__item"><a href="/broad-tags/neurodegeneration" hreflang="en">Neurodegeneration</a></div> </div> </div> </div> </div> </div> Wed, 06 Mar 2024 16:00:00 +0000 adicorat 5556511 at