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      1. Carlos Slim Center for Health Research The Slim Center aims to bring the benefits of genomics-driven medicine to Latin America, gleaning new insights into diseases with relevance to the region.
      2. Gerstner Center for Cancer Diagnostics The Gerstner Center is developing next-generation diagnostic technology for cancer detection and tracking disease progression.
      3. Klarman Cell Observatory The Klarman Cell Observatory is systematically defining mammalian cellular circuits, how they work together to create tissues and organs, and are perturbed to cause disease.
      4. Merkin Institute for Transformative Technologies in Healthcare The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease.
      5. Novo Nordisk Foundation Center for Genomic Mechanisms of Disease This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Ó³»­´«Ã½ and the Danish research community.
      6. Eric and Wendy Schmidt Center The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health.
      7. Stanley Center for Psychiatric Research The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments.
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      1. Art and science connection Explore the connection between art and science and how we bring together artists and Ó³»­´«Ã½ scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations.
      2. Ó³»­´«Ã½ Discovery Center Visit our free public educational space that showcases how researchers at the Ó³»­´«Ã½ and their colleagues around the world seek to understand and treat human disease.
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Functional diversification of dietary plant small molecules by the gut microbiome.
Kuziel GA, Lozano GL, Simian C, et al. Functional diversification of dietary plant small molecules by the gut microbiome. Cell. 2025. doi:10.1016/j.cell.2025.01.045
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Effects of commonly used antibiotics on children's developing gut microbiomes and resistomes in peri-urban Lima, Peru.
Sehgal N, Pajuelo MJ, Gilman RH, et al. Effects of commonly used antibiotics on children’s developing gut microbiomes and resistomes in peri-urban Lima, Peru. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.12.13.24317790
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Response of the gut microbiome and metabolome to dietary fiber in healthy dogs.
Bhosle A, Jackson MI, Walsh AM, Franzosa EA, Badri D V, Huttenhower C. Response of the gut microbiome and metabolome to dietary fiber in healthy dogs. mSystems. 2024:e0045224. doi:10.1128/msystems.00452-24
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Response of the gut microbiome and metabolome to dietary fiber in healthy dogs.
Bhosle A, Jackson MI, Walsh AM, Franzosa EA, Badri D V, Huttenhower C. Response of the gut microbiome and metabolome to dietary fiber in healthy dogs. mSystems. 2024:e0045224. doi:10.1128/msystems.00452-24
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Effects of antibiotic growth promoter and its natural alternative on poultry cecum ecosystem: an integrated analysis of gut microbiota and host expression.
Peng C, Ghanbari M, May A, Abeel T. Effects of antibiotic growth promoter and its natural alternative on poultry cecum ecosystem: an integrated analysis of gut microbiota and host expression. Frontiers in microbiology. 2024;15:1492270. doi:10.3389/fmicb.2024.1492270
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Effects of antibiotic growth promoter and its natural alternative on poultry cecum ecosystem: an integrated analysis of gut microbiota and host expression.
Peng C, Ghanbari M, May A, Abeel T. Effects of antibiotic growth promoter and its natural alternative on poultry cecum ecosystem: an integrated analysis of gut microbiota and host expression. Frontiers in microbiology. 2024;15:1492270. doi:10.3389/fmicb.2024.1492270
Read more
Associations between dietary fibers and gut microbiome composition in the EDIA longitudinal infant cohort.
Lalli MK, Salo TEI, Hakola L, Knip M, Virtanen SM, Vatanen T. Associations between dietary fibers and gut microbiome composition in the EDIA longitudinal infant cohort. The American journal of clinical nutrition. 2024. doi:10.1016/j.ajcnut.2024.11.011
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F. prausnitzii potentially modulates the association between citrus intake and depression.
Samuthpongtorn C, Chan AA, Ma W, et al. F. prausnitzii potentially modulates the association between citrus intake and depression. Microbiome. 2024;12(1):237. doi:10.1186/s40168-024-01961-3
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Spatiotemporal dynamics during niche remodeling by super-colonizing microbiota in the mammalian gut.
Urtecho G, Moody T, Huang Y, et al. Spatiotemporal dynamics during niche remodeling by super-colonizing microbiota in the mammalian gut. Cell systems. 2024. doi:10.1016/j.cels.2024.10.007
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Gut microbial metabolism of bile acids modifies the effect of Mediterranean diet interventions on cardiometabolic risk in a randomized controlled trial.
Gao P, Rinott E, Dong D, et al. Gut microbial metabolism of bile acids modifies the effect of Mediterranean diet interventions on cardiometabolic risk in a randomized controlled trial. Gut microbes. 2024;16(1):2426610. doi:10.1080/19490976.2024.2426610
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In March of 2020, Ó³»­´«Ã½ converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Ó³»­´«Ã½ Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.

In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity.

Through Ó³»­´«Ã½'s Scientists in the Classroom program, Ó³»­´«Ã½ researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

Every summer, 18 high school students spend six weeks at Ó³»­´«Ã½ working side-by-side with mentors on cutting-edge research.

In November 2022, Ó³»­´«Ã½â€™s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Ó³»­´«Ã½â€™s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Ó³»­´«Ã½ has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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