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      1. Carlos Slim Center for Health Research The Slim Center aims to bring the benefits of genomics-driven medicine to Latin America, gleaning new insights into diseases with relevance to the region.
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      3. Klarman Cell Observatory The Klarman Cell Observatory is systematically defining mammalian cellular circuits, how they work together to create tissues and organs, and are perturbed to cause disease.
      4. Merkin Institute for Transformative Technologies in Healthcare The Merkin Institute is supporting early-stage ideas aimed at advancing powerful technological approaches for improving how we understand and treat disease.
      5. Novo Nordisk Foundation Center for Genomic Mechanisms of Disease This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Ó³»­´«Ã½ and the Danish research community.
      6. Eric and Wendy Schmidt Center The EWSC is catalyzing a new field of interdisciplinary research at the intersection of data science and life science, aimed at improving human health.
      7. Stanley Center for Psychiatric Research The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments.
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      1. Art and science connection Explore the connection between art and science and how we bring together artists and Ó³»­´«Ã½ scientists through our artist-in-residence program, gallery exhibitions, and ongoing public conversations.
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Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia.
Wang R, Lu JY, Herbert D, et al. Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia. Human psychopharmacology. 2024:e2898. doi:10.1002/hup.2898
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Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia.
Wang R, Lu JY, Herbert D, et al. Analysis of schizophrenia-associated genetic markers in the HLA region as risk factors for tardive dyskinesia. Human psychopharmacology. 2024:e2898. doi:10.1002/hup.2898
Read more
Genetic Ancestry Markers and Difference in A1c Between African American and White in the Diabetes Prevention Program.
Hivert MF, Christophi CA, Jablonski KA, et al. Genetic Ancestry Markers and Difference in A1c Between African American and White in the Diabetes Prevention Program. J Clin Endocrinol Metab. 2019;104(2):328-336. doi:10.1210/jc.2018-01416
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Adaptive combination of Bayes factors as a powerful method for the joint analysis of rare and common variants.
Lin WY, Chen WJ, Liu CM, et al. Adaptive combination of Bayes factors as a powerful method for the joint analysis of rare and common variants. Sci Rep. 2017;7(1):13858. doi:10.1038/s41598-017-13177-7
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Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type.
Green EK, Di Florio A, Forty L, et al. Genome-wide significant locus for Research Diagnostic Criteria Schizoaffective Disorder Bipolar type. Am J Med Genet B Neuropsychiatr Genet. 2017;174(8):767-771. doi:10.1002/ajmg.b.32572
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Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.
Udler MS, Kim J, von Grotthuss M, et al. Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis. PLoS Med. 2018;15(9):e1002654. doi:10.1371/journal.pmed.1002654
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Using Droplet Digital PCR to Analyze Allele-Specific RNA Expression.
Kamitaki N, Usher CL, McCarroll SA. Using Droplet Digital PCR to Analyze Allele-Specific RNA Expression. Methods Mol Biol. 2018;1768:401-422. doi:10.1007/978-1-4939-7778-9_23
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Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African Anopheles gambiae.
Weetman D, Wilding CS, Neafsey DE, et al. Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African Anopheles gambiae. Sci Rep. 2018;8(1):2920. doi:10.1038/s41598-018-21265-5
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Using expression and genotype to predict drug response in yeast.
Ruderfer DM, Roberts DC, Schreiber SL, Perlstein EO, Kruglyak L. Using expression and genotype to predict drug response in yeast. PLoS One. 2009;4(9):e6907. doi:10.1371/journal.pone.0006907
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Emerging Affinity-Based Proteomic Technologies for Large-Scale Plasma Profiling in Cardiovascular Disease.
Smith G, Gerszten RE. Emerging Affinity-Based Proteomic Technologies for Large-Scale Plasma Profiling in Cardiovascular Disease. Circulation. 2017;135(17):1651-1664. doi:10.1161/CIRCULATIONAHA.116.025446
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In March of 2020, Ó³»­´«Ã½ converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Ó³»­´«Ã½ Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.

In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity.

Through Ó³»­´«Ã½'s Scientists in the Classroom program, Ó³»­´«Ã½ researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

Every summer, 18 high school students spend six weeks at Ó³»­´«Ã½ working side-by-side with mentors on cutting-edge research.

In November 2022, Ó³»­´«Ã½â€™s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Ó³»­´«Ã½â€™s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Ó³»­´«Ã½ has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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