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Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice.

Ron-Harel N, Notarangelo G, Ghergurovich JM, et al. Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice. Proc Natl Acad Sci U S A. 2018;115(52):13347-13352. doi:10.1073/pnas.1804149115

Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment.

Fanning S, Haque A, Imberdis T, et al. Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Mol Cell. 2019;73(5):1001-1014.e8. doi:10.1016/j.molcel.2018.11.028

Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells.

Yang J, Vamvini M, Nigro P, et al. Single-cell dissection of the obesity-exercise axis in adipose-muscle tissues implies a critical role for mesenchymal stem cells. Cell Metab. 2022;34(10):1578-1593.e6. doi:10.1016/j.cmet.2022.09.004

Murine Norovirus Infection Induces T1 Inflammatory Responses to Dietary Antigens.

Bouziat R, Biering SB, Kouame E, et al. Murine Norovirus Infection Induces T1 Inflammatory Responses to Dietary Antigens. Cell Host Microbe. 2018;24(5):677-688.e5. doi:10.1016/j.chom.2018.10.004

Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram.

Biancalani T, Scalia G, Buffoni L, et al. Deep learning and alignment of spatially resolved single-cell transcriptomes with Tangram. Nat Methods. 2021;18(11):1352-1362. doi:10.1038/s41592-021-01264-7

High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy.

Jordi J, Guggiana-Nilo D, Bolton AD, et al. High-throughput screening for selective appetite modulators: A multibehavioral and translational drug discovery strategy. Sci Adv. 2018;4(10):eaav1966. doi:10.1126/sciadv.aav1966

Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression.

Mowery CT, Reyes JM, Cabal-Hierro L, et al. Trisomy of a Down Syndrome Critical Region Globally Amplifies Transcription via HMGN1 Overexpression. Cell Rep. 2018;25(7):1898-1911.e5. doi:10.1016/j.celrep.2018.10.061

ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm.

Gould RA, Aziz H, Woods CE, et al. ROBO4 variants predispose individuals to bicuspid aortic valve and thoracic aortic aneurysm. Nat Genet. 2019;51(1):42-50. doi:10.1038/s41588-018-0265-y

Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons.

Wamsley B, Jaglin XH, Favuzzi E, et al. Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons. Neuron. 2018;100(4):846-859.e7. doi:10.1016/j.neuron.2018.09.026

Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis.

Krahmer N, Najafi B, Schueder F, et al. Organellar Proteomics and Phospho-Proteomics Reveal Subcellular Reorganization in Diet-Induced Hepatic Steatosis. Dev Cell. 2018;47(2):205-221.e7. doi:10.1016/j.devcel.2018.09.017