Aggregating and harmonizing data

Based on the largest resource of its kind, members of the Exome Aggregation Consortium (ExAC) led by scientists at the Ó³»­´«Ã½ of MIT and Harvard report scientific findings from data on the exome sequences (protein-coding portions of the genome) from 60,706 people from diverse ethnic backgrounds. Containing over 10 million DNA variants – many very rare and most identified for the first time – the ExAC dataset is a freely available, high-resolution catalog of human genetic variation that has already made a major impact on clinical research and diagnosis of rare genetic diseases.