Anne Carpenter and Shantanu Singh discuss how they are expanding the uses of their image-based profiling method, Cell Painting, to speed up drug discovery and predict gene function.
Scientists have solved the structure of an important complex of RAS-pathway proteins, explaining how known mutations lead to disease and suggesting potential new binding sites for cancer drugs.
By studying individual cardiac cells from heart failure patients, researchers have identified molecular signatures that point to biological mechanisms of disease.
By introducing cancer-causing mutations into healthy skin cells step-by-step, ӳý scientists have created models of skin cancer that can reveal the effects of mutations.