Illuminating human disease
Genomics is laying the groundwork for a new generation of diagnostics and therapeutics, built on our growing understanding of the biological mechanisms of disease. At the Ó³»´«Ã½, biologists, chemists, physicians, mathematicians, computational biologists, and software engineers are using systematic, unbiased approaches to identify the root causes of disease and find new opportunities for therapeutic intervention. Learn more about #HowWeScience.
Inflammatory bowel disease
Exploring the genetic origins of Crohn’s disease, ulcerative colitis, and related diseases to better prevent and treat them
Inflammatory bowel disease (IBD) — a term that includes both ulcerative colitis and Crohn's disease — occurs when the immune system is overactive in the gut. As a result, the digestive tract becomes chronically inflamed, leading to serious health issues for patients. At the Ó³»´«Ã½, scientists combine human genetics, genetic and chemical screens, population studies, and deep insights into the microbiome to uncover the basic mechanisms of IBD and other related immune disorders. A better understanding of the genetic, molecular, microbial, and cellular roots of IBD could lead to new ways of diagnosing and treating these conditions.
