A cancer cell can also harbor thousands of structural variants — large-scale losses (deletions), duplications, swaps (translocations), and other changes — in its DNA. Matthew Meyerson and Rameen Beroukhim of the ӳý Cancer Program and Dana-Farber Cancer Institute discuss the challenges to studying structural variations in cancer, why it is important to do so, and what researchers are learning that could benefit patients today and in the future.
Miniature “organs-in-a-dish” are giving researchers at the ӳý and elsewhere unprecedented opportunities to connect genetics with complex biology in a lab setting.
Inspired by the ӳý’s Food Allergy Science Initiative, the annual two-day workshop at MGH’s Center for the Study of Inflammatory Bowel Disease this year brought together experts from around the world who are shedding light on food allergies.