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Sit. Fetch. Roll-over. Humans have been trying to teach dogs for tens of thousands of years. But when it comes to the genetics of cancer, it turns out dogs have a lot to teach us, as well.

Different as we may seem, humans and dogs are genetically-speaking quite similar. Almost all canine genes have a matching gene in the human genome. Given this correlation, it’s no surprise that dogs suffer from many of the same genetic disorders as human, including cancer.

In his September 13, TEDxCambridge lecture, ‘Decoding a Genomic Revolution,’ Ó³»­´«Ã½ associate member and MIT associate professor Manolis Kellis used details from his own genome to demonstrate how science can bridge the gap between genetic variants and disease.

Check out the video below and accompany Kellis on a journey into his personal genome to find out how recent discoveries could change the future of medical care.