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Metabolomics Platform

Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability.

Abbott KL, Ali A, Reinfeld BI, et al. Metabolite profiling of human renal cell carcinoma reveals tissue-origin dominance in nutrient availability. eLife. 2024;13. doi:10.7554/eLife.95652

ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits.

Singh C, Jin B, Shrestha N, et al. ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits. Cell metabolism. 2024;36(1):144-158.e7. doi:10.1016/j.cmet.2023.11.010

Associations between cord blood acetaminophen biomarkers and childhood asthma with and without allergic comorbidities.

Li Y, Hong X, Chandran A, et al. Associations between cord blood acetaminophen biomarkers and childhood asthma with and without allergic comorbidities. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology. 2024. doi:10.1016/j.anai.2024.03.001

ANGPTL3 regulates the peroxisomal translocation of SmarcAL1 in response to cell growth states.

Nagai TH, Mizoguchi T, Wang Y, et al. ANGPTL3 regulates the peroxisomal translocation of SmarcAL1 in response to cell growth states. bioRxiv : the preprint server for biology. 2024. doi:10.1101/2024.06.03.597253

Metabolites Associated With Uremic Symptoms in Patients With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.

Wulczyn KE, Shafi T, Anderson A, et al. Metabolites Associated With Uremic Symptoms in Patients With CKD: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2024. doi:10.1053/j.ajkd.2023.11.013

Human metabolic chambers reveal a coordinated metabolic-physiologic response to nutrition.

Perry AS, Piaggi P, Huang S, et al. Human metabolic chambers reveal a coordinated metabolic-physiologic response to nutrition. medRxiv : the preprint server for health sciences. 2024. doi:10.1101/2024.04.08.24305087

Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia.

Mondal AK, Brock DC, Rowan S, et al. Selective transcriptomic dysregulation of metabolic pathways in liver and retina by short- and long-term dietary hyperglycemia. iScience. 2024;27(2):108979. doi:10.1016/j.isci.2024.108979

Plasma metabolites and physical function in patients undergoing hemodialysis.

Moorthi RN, Moe SM, O’Connell T, et al. Plasma metabolites and physical function in patients undergoing hemodialysis. Scientific reports. 2024;14(1):8427. doi:10.1038/s41598-024-58522-9

Discovery and validation of plasma, saliva and multi-fluid plasma-saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults.

Haslam DE, Liang L, Guo K, et al. Discovery and validation of plasma, saliva and multi-fluid plasma-saliva metabolomic scores predicting insulin resistance and diabetes progression or regression among Puerto Rican adults. Diabetologia. 2024. doi:10.1007/s00125-024-06169-6

Tryptophan-kynurenine metabolic pathway and daytime dysfunction in women with HIV.

Shorer EF, Rubin LH, French AL, et al. Tryptophan-kynurenine metabolic pathway and daytime dysfunction in women with HIV. Journal of neurovirology. 2024. doi:10.1007/s13365-024-01195-x