Making Biological Sense of GWAS Data: Lessons from the FTO Locus.

Cell Metab
Authors
Keywords
Abstract

GWAS have yielded many candidate loci for complex diseases like obesity, but interpreting the biological context of these findings has been difficult. Claussnitzer et al. (2015) use a sophisticated combination of bioinformatic and experimental approaches to address this bottleneck for variants in the FTO locus that associate with obesity.

Year of Publication
2015
Journal
Cell Metab
Volume
22
Issue
4
Pages
538-9
Date Published
2015 Oct 6
ISSN
1932-7420
DOI
10.1016/j.cmet.2015.09.018
PubMed ID
26445508
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