Sequencing of Culex quinquefasciatus establishes a platform for mosquito comparative genomics.
| Authors | |
| Keywords | |
| Abstract | Culex quinquefasciatus (the southern house mosquito) is an important mosquito vector of viruses such as West Nile virus and St. Louis encephalitis virus, as well as of nematodes that cause lymphatic filariasis. C. quinquefasciatus is one species within the Culex pipiens species complex and can be found throughout tropical and temperate climates of the world. The ability of C. quinquefasciatus to take blood meals from birds, livestock, and humans contributes to its ability to vector pathogens between species. Here, we describe the genomic sequence of C. quinquefasciatus: Its repertoire of 18,883 protein-coding genes is 22% larger than that of Aedes aegypti and 52% larger than that of Anopheles gambiae with multiple gene-family expansions, including olfactory and gustatory receptors, salivary gland genes, and genes associated with xenobiotic detoxification. |
| Year of Publication | 2010
|
| Journal | Science
|
| Volume | 330
|
| Issue | 6000
|
| Pages | 86-8
|
| Date Published | 2010 Oct 1
|
| ISSN | 1095-9203
|
| DOI | 10.1126/science.1191864
|
| PubMed ID | 20929810
|
| PubMed Central ID | PMC3740384
|
| Links | |
| Grant list | HHSN266200400001C / PHS HHS / United States
HHSN266200400039C / AI / NIAID NIH HHS / United States
HHSN266200400039C / PHS HHS / United States
N01-AI-30071 / AI / NIAID NIH HHS / United States
N01AI30071 / AI / NIAID NIH HHS / United States
ZIA AI000810-13 / Intramural NIH HHS / United States
|