Taking on the Elephant in the Tissue Culture Room: iPSC Modeling for Sporadic ALS.
Cell Stem Cell
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| Abstract | Modeling ALS remains a major challenge since the vast majority of cases are sporadic. Recently in Nature Medicine, Fujimori et al. leverage genetic heterogeneity and define subgroups of iPSC-derived motor neurons using multiplex phenotypic profiles, and thus make substantial progress toward robust modeling of both familial and sporadic ALS. |
| Year of Publication | 2018
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| Journal | Cell Stem Cell
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| Volume | 23
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| Issue | 4
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| Pages | 466-467
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| Date Published | 2018 10 04
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| ISSN | 1875-9777
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| DOI | 10.1016/j.stem.2018.09.015
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| PubMed ID | 30290176
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