TREM2: Keeping Microglia Fit during Good Times and Bad.
Cell Metab
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| Abstract | Microglia are the macrophages of the brain and play an important role in Alzheimer's disease (AD). In Cell, Ulland et al. (2017) recently reported that mutations in TREM2, a protein implicated in AD, disrupt microglial energy state and function, thus sabotaging the microglia's ability to defend the brain against amyloid plaques. |
| Year of Publication | 2017
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| Journal | Cell Metab
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| Volume | 26
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| Issue | 4
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| Pages | 590-591
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| Date Published | 2017 Oct 03
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| ISSN | 1932-7420
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| DOI | 10.1016/j.cmet.2017.09.010
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| PubMed ID | 28978423
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