Unraveling the Functional Heterogeneity of Human Skin at Single-Cell Resolution.
Hematology/oncology clinics of North America
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Abstract | The skin consists of several cell populations, including epithelial, immune, and stromal cells. Recently, there has been a significant increase in single-cell RNA-sequencing studies, contributing to the development of a consensus Human Skin Cell Atlas. The aim is to understand skin biology better and identify potential therapeutic targets. The present review utilized previously published single-cell RNA-sequencing datasets to explore human skin's cellular and functional heterogeneity. Additionally, it summarizes the functional significance of newly identified cell subpopulations in processes such as wound healing and aging. |
Year of Publication | 2024
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Journal | Hematology/oncology clinics of North America
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Date Published | 06/2024
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ISSN | 1558-1977
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DOI | 10.1016/j.hoc.2024.05.001
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PubMed ID | 38839486
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