High Prevalence of Carbapenem-resistant in Fecal and Water Samples in Dhaka, Bangladesh.
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Abstract | We evaluated (Kp) gut carriage in healthy, unrelated adults and children living in separate households in Dhaka, Bangladesh. Average Kp prevalence in stool samples ranged from 61% in young children (15/25) to 81% in adults (21/26), with significantly higher abundance in adults ( = .03, -test). Kp was also prevalent in household water (64%, 21/33) and standing water (85%, 23/27). The presence of Kp in household water was not strongly linked to stool Kp abundance among household members. Antimicrobial resistance was notable: 9% (6/69) of stool and 16% (7/44) of water isolates exhibited multidrug resistance. Carbapenem resistance was observed in 12% of stool isolates (8/69) and 14% of water isolates (6/44). These findings underscore the commonality of Kp in human and environmental reservoirs in Dhaka, Bangladesh, and highlight the emergence of drug-resistant Kp beyond healthcare settings. |
Year of Publication | 2024
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Journal | Open forum infectious diseases
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Volume | 11
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Issue | 11
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Pages | ofae612
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Date Published | 11/2024
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ISSN | 2328-8957
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DOI | 10.1093/ofid/ofae612
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PubMed ID | 39494455
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