Homeotic Transformations of Neuronal Cell Identities.
Trends Neurosci
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| Abstract | Homeosis is classically defined as the transformation of one body part into something that resembles another body part. We propose here to broaden the concept of homeosis to the many neuronal cell identity transformations that have been uncovered over the past few years upon removal of specific regulatory factors in organisms from Caenorhabditis elegans to Drosophila, zebrafish, and mice. The concept of homeosis provides a framework for the evolution of cell type diversity in the brain. |
| Year of Publication | 2015
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| Journal | Trends Neurosci
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| Volume | 38
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| Issue | 12
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| Pages | 751-62
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| Date Published | 2015 Dec
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| ISSN | 1878-108X
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| DOI | 10.1016/j.tins.2015.10.005
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| PubMed ID | 26596501
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| Grant list | R01MH101268 / MH / NIMH NIH HHS / United States
R01NS078164 / NS / NINDS NIH HHS / United States
R37NS039996 / NS / NINDS NIH HHS / United States
Howard Hughes Medical Institute / United States
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