Dissecting the human microbiome with single-cell genomics.
Genome Med
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Abstract | Recent advances in genome sequencing of single microbial cells enable the assignment of functional roles to members of the human microbiome that cannot currently be cultured. This approach can reveal the genomic basis of phenotypic variation between closely related strains and can be applied to the targeted study of immunogenic bacteria in disease. |
Year of Publication | 2017
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Journal | Genome Med
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Volume | 9
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Issue | 1
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Pages | 56
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Date Published | 2017 06 14
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ISSN | 1756-994X
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DOI | 10.1186/s13073-017-0448-7
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PubMed ID | 28615076
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PubMed Central ID | PMC5471897
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Grant list | P30 DK043351 / DK / NIDDK NIH HHS / United States
U54 DK102557 / DK / NIDDK NIH HHS / United States
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