Dissecting the human microbiome with single-cell genomics.

Genome Med
Authors
Keywords
Abstract

Recent advances in genome sequencing of single microbial cells enable the assignment of functional roles to members of the human microbiome that cannot currently be cultured. This approach can reveal the genomic basis of phenotypic variation between closely related strains and can be applied to the targeted study of immunogenic bacteria in disease.

Year of Publication
2017
Journal
Genome Med
Volume
9
Issue
1
Pages
56
Date Published
2017 06 14
ISSN
1756-994X
DOI
10.1186/s13073-017-0448-7
PubMed ID
28615076
PubMed Central ID
PMC5471897
Links
Grant list
P30 DK043351 / DK / NIDDK NIH HHS / United States
U54 DK102557 / DK / NIDDK NIH HHS / United States