Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea.

Nat Biotechnol
Authors
Keywords
Abstract

We present two standards developed by the Genomic Standards Consortium (GSC) for reporting bacterial and archaeal genome sequences. Both are extensions of the Minimum Information about Any (x) Sequence (MIxS). The standards are the Minimum Information about a Single Amplified Genome (MISAG) and the Minimum Information about a Metagenome-Assembled Genome (MIMAG), including, but not limited to, assembly quality, and estimates of genome completeness and contamination. These standards can be used in combination with other GSC checklists, including the Minimum Information about a Genome Sequence (MIGS), Minimum Information about a Metagenomic Sequence (MIMS), and Minimum Information about a Marker Gene Sequence (MIMARKS). Community-wide adoption of MISAG and MIMAG will facilitate more robust comparative genomic analyses of bacterial and archaeal diversity.

Year of Publication
2017
Journal
Nat Biotechnol
Volume
35
Issue
8
Pages
725-731
Date Published
2017 Aug 08
ISSN
1546-1696
DOI
10.1038/nbt.3893
PubMed ID
28787424
PubMed Central ID
PMC6436528
Links
Grant list
310039 / European Research Council / International
R01 AI123037 / AI / NIAID NIH HHS / United States
R01 DE024463 / DE / NIDCR NIH HHS / United States