Genetic and epigenetic studies of adiposity and cardiometabolic disease.
Genome Med
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| Abstract | Over 300 million adults are obese, but little is known about the impact of obesity on cardiovascular health. We discuss recent genetic and epigenetic studies of adiposity that indicate a causal role for general and central adiposity in cardiometabolic disease, and highlight potential mechanisms including insulin resistance and gene expression. |
| Year of Publication | 2017
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| Journal | Genome Med
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| Volume | 9
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| Issue | 1
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| Pages | 82
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| Date Published | 2017 09 18
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| ISSN | 1756-994X
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| DOI | 10.1186/s13073-017-0474-5
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| PubMed ID | 28923095
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| PubMed Central ID | PMC5604307
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| Grant list | M01 RR000070 / RR / NCRR NIH HHS / United States
Medical Research Council / United Kingdom
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