RANGER-DTL 2.0: rigorous reconstruction of gene-family evolution by duplication, transfer and loss.

Bioinformatics
Authors
Keywords
Abstract

Summary: RANGER-DTL 2.0 is a software program for inferring gene family evolution using Duplication-Transfer-Loss reconciliation. This new software is highly scalable and easy to use, and offers many new features not currently available in any other reconciliation program. RANGER-DTL 2.0 has a particular focus on reconciliation accuracy and can account for many sources of reconciliation uncertainty including uncertain gene tree rooting, gene tree topological uncertainty, multiple optimal reconciliations and alternative event cost assignments. RANGER-DTL 2.0 is open-source and written in C++ and Python.

Availability and implementation: Pre-compiled executables, source code (open-source under GNU GPL) and a detailed manual are freely available from .

Supplementary information: Supplementary data are available at Bioinformatics online.

Year of Publication
2018
Journal
Bioinformatics
Volume
34
Issue
18
Pages
3214-3216
Date Published
2018 09 15
ISSN
1367-4811
DOI
10.1093/bioinformatics/bty314
PubMed ID
29688310
PubMed Central ID
PMC6137995
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