Haematological malignancies: at the forefront of immunotherapeutic innovation.
Nat Rev Cancer
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Abstract | The recent successes of cancer immunotherapies have stimulated interest in the potential widespread application of these approaches; haematological malignancies have provided both initial proofs of concept and an informative testing ground for various immune-based therapeutics. The immune-cell origin of many of the blood malignancies provides a unique opportunity both to understand the mechanisms of cancer immune responsiveness and immune evasion, and to exploit these mechanisms for therapeutic purposes. |
Year of Publication | 2015
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Journal | Nat Rev Cancer
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Volume | 15
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Issue | 4
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Pages | 201-15
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Date Published | 2015 Apr
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ISSN | 1474-1768
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URL | |
DOI | 10.1038/nrc3907
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PubMed ID | 25786696
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PubMed Central ID | PMC4511812
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Grant list | 1R01CA155010-02 / CA / NCI NIH HHS / United States
U54 HG003067 / HG / NHGRI NIH HHS / United States
R01 HL103532 / HL / NHLBI NIH HHS / United States
U54HG003067 / HG / NHGRI NIH HHS / United States
T32CA009172 / CA / NCI NIH HHS / United States
T32 CA009172 / CA / NCI NIH HHS / United States
R01 CA155010 / CA / NCI NIH HHS / United States
5R01HL103532-03 / HL / NHLBI NIH HHS / United States
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