Cancer and the microbiota.

Science
Authors
Keywords
Abstract

A host's microbiota may increase, diminish, or have no effect at all on cancer susceptibility. Assigning causal roles in cancer to specific microbes and microbiotas, unraveling host-microbiota interactions with environmental factors in carcinogenesis, and exploiting such knowledge for cancer diagnosis and treatment are areas of intensive interest. This Review considers how microbes and the microbiota may amplify or mitigate carcinogenesis, responsiveness to cancer therapeutics, and cancer-associated complications.

Year of Publication
2015
Journal
Science
Volume
348
Issue
6230
Pages
80-6
Date Published
2015 Apr 03
ISSN
1095-9203
URL
DOI
10.1126/science.aaa4972
PubMed ID
25838377
Links
Grant list
R01CA154426 / CA / NCI NIH HHS / United States