ERBB2 emerges as a new target for colorectal cancer.

Cancer Discov
Authors
Keywords
Abstract

ERBB2 mutations and amplifications are present in 7% of colorectal cancers. The presence of these alterations may be a marker of resistance to anti-EGFR therapy and, more importantly, could help identify patients who would benefit from ERBB2-directed therapy.

Year of Publication
2015
Journal
Cancer Discov
Volume
5
Issue
8
Pages
799-801
Date Published
2015 Aug
ISSN
2159-8290
URL
DOI
10.1158/2159-8290.CD-15-0730
PubMed ID
26243861
PubMed Central ID
PMC4527096
Links
Grant list
K08 CA134931 / CA / NCI NIH HHS / United States
P01 CA098101 / CA / NCI NIH HHS / United States
P01CA098101 / CA / NCI NIH HHS / United States