Splice it up: Atypical transcripts to boost leukemia immunotherapy.

Immunity
Authors
Abstract

Neoantigens are prime targets for cancer immunotherapy, but their identification in low mutational burden malignancies remains challenging. In this issue of Immunity, Ehx et al. show that atypical transcripts, and particularly retained introns, expand the spectrum of leukemia immunotherapy targets.

Year of Publication
2021
Journal
Immunity
Volume
54
Issue
4
Pages
608-610
Date Published
2021 Apr 13
ISSN
1097-4180
DOI
10.1016/j.immuni.2021.03.016
PubMed ID
33852826
Links