Cell STRAINER (STRAin INstability profilER) is a web portal designed to assess the discordance between a given cell line sample to its reference sample, as was characterized by the Cancer Cell Line Encyclopedia (CCLE). Users can upload cell line copy number data to assess their strain’s genetic distance from the CCLE reference strain. This genetic distance is a good indicator of gene expression and drug response distances.
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Topic
cell lines
Cancer
copy number variation
genomic instability
genomics