Immune repertoires: specificity and dynamics
Aleksandra Walczak
CNRS ENS
The immune repertoire responds to a wide variety of pathogenic threats. Immune repertoire sequencing experiments give us insight into the composition of these repertoires. Since the functioning of the repertoire relies on statistical properties, statistical analysis is needed to identify responding clones. Using such methods I will describe the repertoire level response to vaccination and auto-immune disease. More generally, I will describe methods that allow us to describe the statistics of immune repertoires and give insight into their development.