Ó³»­´«Ã½

This presentation was filmed during the March 2015 Fragment-based Drug Discovery 101 workshop, part of the Ó³»­´«Ã½E Workshop series.

This seminar highlighted key concepts relevant for implementing Fragment Based Drug Discovery (FBDD) and Structure-Based Drug Design (SBD), approaches to efficient discovery and optimization of drugs for newly identified and challenging targets.

Major topics include:

• Key factors that motivate FBDD and SBD
• Physicochemical properties and chemical space
• NMR methods for screening and structure-based design
• Other biophysical methods for screening and structure-based design
• Examples of success in the clinic