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“Population descriptors” — including race, ethnicity, and genetic ancestry — can broadly be thought of as describing “descent-associated” groups, whose members are thought to share some characteristic that derives from their common origin. These descriptors are used ubiquitously across genetics and genomics research. However, inappropriate use of these terms, without proper contextualization, can make problematic essentialist links to biology and propagate incorrect and racist notions that discrete genetic groups exist. In an effort to address these problems, the NASEM formed a working group to create guidance about the use of population descriptors as well as an opportunity to implement substantive changes to the ways they are used. Join Katrina Claw (University of Colorado Anschutz Medical Campus), Genevieve L. Wojcik (Johns Hopkins Bloomberg School of Public Health), and Anna Lewis (Edmond and Lily Safra Center for Ethics, Harvard University and ӳ����ý) for a panel discussion on why using group descriptors thoughtfully is important for science and society and what researchers should consider when making these decisions in their own work.