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Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life.

Song M, Zheng Y, Qi L, Hu FB, Chan AT, Giovannucci EL. Longitudinal Analysis of Genetic Susceptibility and BMI Throughout Adult Life. Diabetes. 2018;67(2):248-255. doi:10.2337/db17-1156

Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly.

Aneichyk T, Hendriks WT, Yadav R, et al. Dissecting the Causal Mechanism of X-Linked Dystonia-Parkinsonism by Integrating Genome and Transcriptome Assembly. Cell. 2018;172(5):897-909.e21. doi:10.1016/j.cell.2018.02.011

Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke.

Phuah CL, Dave T, Malik R, et al. Genetic variants influencing elevated myeloperoxidase levels increase risk of stroke. Brain. 2017;140(10):2663-2672. doi:10.1093/brain/awx220

Time-averaged disease activity fits better joint destruction in rheumatoid arthritis.

Tsuji H, Yano K, Furu M, et al. Time-averaged disease activity fits better joint destruction in rheumatoid arthritis. Sci Rep. 2017;7(1):5856. doi:10.1038/s41598-017-05581-w

Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course.

Schirmer M, Denson L, Vlamakis H, et al. Compositional and Temporal Changes in the Gut Microbiome of Pediatric Ulcerative Colitis Patients Are Linked to Disease Course. Cell Host Microbe. 2018;24(4):600-610.e4. doi:10.1016/j.chom.2018.09.009

Genetic Evidence That Carbohydrate-Stimulated Insulin Secretion Leads to Obesity.

Astley CM, Todd JN, Salem RM, et al. Genetic Evidence That Carbohydrate-Stimulated Insulin Secretion Leads to Obesity. Clin Chem. 2018;64(1):192-200. doi:10.1373/clinchem.2017.280727

Genome-wide association study of depressive symptoms in the Hispanic Community Health Study/Study of Latinos.

Dunn EC, Sofer T, Wang MJ, et al. Genome-wide association study of depressive symptoms in the Hispanic Community Health Study/Study of Latinos. J Psychiatr Res. 2018;99:167-176. doi:10.1016/j.jpsychires.2017.12.010

Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci.

Tanskanen T, van den Berg L, Välimäki N, et al. Genome-wide association study and meta-analysis in Northern European populations replicate multiple colorectal cancer risk loci. Int J Cancer. 2018;142(3):540-546. doi:10.1002/ijc.31076

Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair.

Haradhvala NJ, Kim J, Maruvka YE, et al. Distinct mutational signatures characterize concurrent loss of polymerase proofreading and mismatch repair. Nat Commun. 2018;9(1):1746. doi:10.1038/s41467-018-04002-4

Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis.

Udler MS, Kim J, von Grotthuss M, et al. Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis. PLoS Med. 2018;15(9):e1002654. doi:10.1371/journal.pmed.1002654