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Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects.

Hu R, Morley MP, Brandimarto J, et al. Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects. Circ Genom Precis Med. 2018;11(3):e001901. doi:10.1161/CIRCGEN.117.001901

A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease.

Hrdlickova B, Mulder CJ, Malamut G, et al. A locus at 7p14.3 predisposes to refractory celiac disease progression from celiac disease. Eur J Gastroenterol Hepatol. 2018;30(8):828-837. doi:10.1097/MEG.0000000000001168

Discovery of novel heart rate-associated loci using the Exome Chip.

Van Den Berg ME, Warren HR, Cabrera CP, et al. Discovery of novel heart rate-associated loci using the Exome Chip. Hum Mol Genet. 2017;26(12):2346-2363. doi:10.1093/hmg/ddx113

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders.

Weiner DJ, Wigdor EM, Ripke S, et al. Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. Nat Genet. 2017;49(7):978-985. doi:10.1038/ng.3863

Evaluating the Impact of Functional Genetic Variation on HIV-1 Control.

McLaren PJ, Pulit SL, Gurdasani D, et al. Evaluating the Impact of Functional Genetic Variation on HIV-1 Control. J Infect Dis. 2017;216(9):1063-1069. doi:10.1093/infdis/jix470

A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder.

Polimanti R, Amstadter AB, Stein MB, et al. A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder. Genome Med. 2017;9(1):99. doi:10.1186/s13073-017-0491-4

Genomic Influences on Susceptibility and Severity of Rheumatoid Arthritis.

Knevel R, Huizinga TWJ, Kurreeman F. Genomic Influences on Susceptibility and Severity of Rheumatoid Arthritis. Rheum Dis Clin North Am. 2017;43(3):347-361. doi:10.1016/j.rdc.2017.04.002

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis.

Manousaki D, Dudding T, Haworth S, et al. Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis. Am J Hum Genet. 2017;101(2):227-238. doi:10.1016/j.ajhg.2017.06.014

Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer.

Yurgelun MB, Chittenden AB, Morales-Oyarvide V, et al. Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer. Genet Med. 2019;21(1):213-223. doi:10.1038/s41436-018-0009-5

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder.

Demontis D, Walters RK, Martin J, et al. Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder. Nat Genet. 2019;51(1):63-75. doi:10.1038/s41588-018-0269-7