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Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes.

Majithia AR, Flannick J, Shahinian P, et al. Rare variants in PPARG with decreased activity in adipocyte differentiation are associated with increased risk of type 2 diabetes. Proc Natl Acad Sci U S A. 2014;111(36):13127-32. doi:10.1073/pnas.1410428111

Variation at HLA-DRB1 is associated with resistance to enteric fever.

Dunstan SJ, Hue NT, Han B, et al. Variation at HLA-DRB1 is associated with resistance to enteric fever. Nat Genet. 2014;46(12):1333-6. doi:10.1038/ng.3143

Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.

Tonomura N, Elvers I, Thomas R, et al. Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers. PLoS Genet. 2015;11(2):e1004922. doi:10.1371/journal.pgen.1004922

The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease.

Moutsianas L, Agarwala V, Fuchsberger C, et al. The power of gene-based rare variant methods to detect disease-associated variation and test hypotheses about complex disease. PLoS Genet. 2015;11(4):e1005165. doi:10.1371/journal.pgen.1005165

African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans.

Tandon A, Chen CJ, Penman A, et al. African Ancestry Analysis and Admixture Genetic Mapping for Proliferative Diabetic Retinopathy in African Americans. Invest Ophthalmol Vis Sci. 2015;56(6):3999-4005. doi:10.1167/iovs.15-16674

A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12.

Bianchi M, Dahlgren S, Massey J, et al. A Multi-Breed Genome-Wide Association Analysis for Canine Hypothyroidism Identifies a Shared Major Risk Locus on CFA12. PLoS One. 2015;10(8):e0134720. doi:10.1371/journal.pone.0134720

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Day FR, Ruth KS, Thompson DJ, et al. Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat Genet. 2015;47(11):1294-303. doi:10.1038/ng.3412

Large Scale Genetic Research on Neuropsychiatric Disorders in African Populations is Needed.

Dalvie S, Koen N, Duncan L, et al. Large Scale Genetic Research on Neuropsychiatric Disorders in African Populations is Needed. EBioMedicine. 2015;2(10):1259-61. doi:10.1016/j.ebiom.2015.10.002

Reclassification of genetic-based risk predictions as GWAS data accumulate.

Krier J, Barfield R, Green RC, Kraft P. Reclassification of genetic-based risk predictions as GWAS data accumulate. Genome Med. 2016;8(1):20. doi:10.1186/s13073-016-0272-5

The genomic landscape of juvenile myelomonocytic leukemia.

Stieglitz E, Taylor-Weiner AN, Chang TY, et al. The genomic landscape of juvenile myelomonocytic leukemia. Nat Genet. 2015;47(11):1326-1333. doi:10.1038/ng.3400