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Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages.

Schafer DP, Stevens B. Brains, Blood, and Guts: MeCP2 Regulates Microglia, Monocytes, and Peripheral Macrophages. Immunity. 2015;42(4):600-2. doi:10.1016/j.immuni.2015.04.002

A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase.

Brandish PE, Chiu CS, Schneeweis J, et al. A cell-based ultra-high-throughput screening assay for identifying inhibitors of D-amino acid oxidase. J Biomol Screen. 2006;11(5):481-7. doi:10.1177/1087057106288181

High-affinity cooperative Ca binding by MICU1-MICU2 serves as an on-off switch for the uniporter.

Kamer KJ, Grabarek Z, Mootha VK. High-affinity cooperative Ca binding by MICU1-MICU2 serves as an on-off switch for the uniporter. EMBO Rep. 2017;18(8):1397-1411. doi:10.15252/embr.201643748

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia.

Witt SH, Streit F, Jungkunz M, et al. Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia. Transl Psychiatry. 2017;7(6):e1155. doi:10.1038/tp.2017.115

IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment.

Nirschl CJ, Suárez-Fariñas M, Izar B, et al. IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment. Cell. 2017;170(1):127-141.e15. doi:10.1016/j.cell.2017.06.016

Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia.

Wang L, Fan J, Francis JM, et al. Integrated single-cell genetic and transcriptional analysis suggests novel drivers of chronic lymphocytic leukemia. Genome Res. 2017;27(8):1300-1311. doi:10.1101/gr.217331.116

Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons.

Zdraljevic S, Strand C, Seidel HS, Cook DE, Doench JG, Andersen EC. Natural variation in a single amino acid substitution underlies physiological responses to topoisomerase II poisons. PLoS Genet. 2017;13(7):e1006891. doi:10.1371/journal.pgen.1006891

The role of de novo mutations in the development of amyotrophic lateral sclerosis.

van Doormaal PTC, Ticozzi N, Weishaupt JH, et al. The role of de novo mutations in the development of amyotrophic lateral sclerosis. Hum Mutat. 2017;38(11):1534-1541. doi:10.1002/humu.23295

is a colitis risk gene that regulates stability of epithelial adherens junctions.

Mohanan V, Nakata T, Desch N, et al. is a colitis risk gene that regulates stability of epithelial adherens junctions. Science. 2018;359(6380):1161-1166. doi:10.1126/science.aan0814

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

Demenais F, Margaritte-Jeannin P, Barnes KC, et al. Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nat Genet. 2018;50(1):42-53. doi:10.1038/s41588-017-0014-7