Sawcer S, Ban M, Maranian M, et al. A high-density screen for linkage in multiple sclerosis. Am J Hum Genet. 2005;77(3):454-67. doi:10.1086/444547
Kleinewietfeld M, Hafler DA. Regulatory T cells in autoimmune neuroinflammation. Immunol Rev. 2014;259(1):231-44. doi:10.1111/imr.12169
Sawcer SJ, Maranian M, Singlehurst S, et al. Enhancing linkage analysis of complex disorders: an evaluation of high-density genotyping. Hum Mol Genet. 2004;13(17):1943-9. doi:10.1093/hmg/ddh202
Xiao S, Yosef N, Yang J, et al. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms. Immunity. 2014;40(4):477-89. doi:10.1016/j.immuni.2014.04.004
Fancy SPJ, Harrington EP, Yuen TJ, et al. Axin2 as regulatory and therapeutic target in newborn brain injury and remyelination. Nat Neurosci. 2011;14(8):1009-16. doi:10.1038/nn.2855
Paraboschi EM, Rimoldi V, Soldà G, et al. Functional variations modulating PRKCA expression and alternative splicing predispose to multiple sclerosis. Hum Mol Genet. 2014;23(25):6746-61. doi:10.1093/hmg/ddu392
Fancy SPJ, Kotter MR, Harrington EP, et al. Overcoming remyelination failure in multiple sclerosis and other myelin disorders. Exp Neurol. 2010;225(1):18-23. doi:10.1016/j.expneurol.2009.12.020
Hayeck TJ, Zaitlen NA, Loh PR, et al. Mixed model with correction for case-control ascertainment increases association power. Am J Hum Genet. 2015;96(5):720-30. doi:10.1016/j.ajhg.2015.03.004
Patsopoulos NA, Bayer Pharma MS Genetics Working Group, Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist, et al. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol. 2011;70(6):897-912. doi:10.1002/ana.22609
Cao Y, Goods BA, Raddassi K, et al. Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis. Sci Transl Med. 2015;7(287):287ra74. doi:10.1126/scitranslmed.aaa8038