Fonseka CY, Rao DA, Raychaudhuri S. Leveraging blood and tissue CD4+ T cell heterogeneity at the single cell level to identify mechanisms of disease in rheumatoid arthritis. Curr Opin Immunol. 2017;49:27-36. doi:10.1016/j.coi.2017.08.005
Palmer WS, Poncet-Montange G, Liu G, et al. Structure-Guided Design of IACS-9571, a Selective High-Affinity Dual TRIM24-BRPF1 Bromodomain Inhibitor. J Med Chem. 2016;59(4):1440-54. doi:10.1021/acs.jmedchem.5b00405
Zelikowsky M, Hui M, Karigo T, et al. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell. 2018;173(5):1265-1279.e19. doi:10.1016/j.cell.2018.03.037
Wyant GA, Abu-Remaileh M, Wolfson RL, et al. mTORC1 Activator SLC38A9 Is Required to Efflux Essential Amino Acids from Lysosomes and Use Protein as a Nutrient. Cell. 2017;171(3):642-654.e12. doi:10.1016/j.cell.2017.09.046
Hangauer MJ, Viswanathan VS, Ryan MJ, et al. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition. Nature. 2017;551(7679):247-250. doi:10.1038/nature24297
Dvela-Levitt M, Kost-Alimova M, Emani M, et al. Small Molecule Targets TMED9 and Promotes Lysosomal Degradation to Reverse Proteinopathy. Cell. 2019;178(3):521-535.e23. doi:10.1016/j.cell.2019.07.002
Halassa MM, Kastner S. Thalamic functions in distributed cognitive control. Nat Neurosci. 2017;20(12):1669-1679. doi:10.1038/s41593-017-0020-1
Martin-Malpartida P, Batet M, Kaczmarska Z, et al. Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun. 2017;8(1):2070. doi:10.1038/s41467-017-02054-6
Pregizer SK, Kiapour AM, Young M, et al. Impact of broad regulatory regions on Gdf5 expression and function in knee development and susceptibility to osteoarthritis. Ann Rheum Dis. 2018;77(3):450. doi:10.1136/annrheumdis-2017-212475
Dolciami D, Gargaro M, Cerra B, et al. Binding Mode and Structure-Activity Relationships of ITE as an Aryl Hydrocarbon Receptor (AhR) Agonist. ChemMedChem. 2018;13(3):270-279. doi:10.1002/cmdc.201700669