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A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration.

Gräff J, Kahn M, Samiei A, et al. A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration. J Neurosci. 2013;33(21):8951-60. doi:10.1523/JNEUROSCI.5657-12.2013

High-throughput genetic screen for synaptogenic factors: identification of LRP6 as critical for excitatory synapse development.

Sharma K, Choi SY, Zhang Y, et al. High-throughput genetic screen for synaptogenic factors: identification of LRP6 as critical for excitatory synapse development. Cell Rep. 2013;5(5):1330-41. doi:10.1016/j.celrep.2013.11.008

De novo mutations in schizophrenia implicate synaptic networks.

Fromer M, Pocklington AJ, Kavanagh DH, et al. De novo mutations in schizophrenia implicate synaptic networks. Nature. 2014;506(7487):179-84. doi:10.1038/nature12929

High content image analysis identifies novel regulators of synaptogenesis in a high-throughput RNAi screen of primary neurons.

Nieland TJF, Logan DJ, Saulnier J, et al. High content image analysis identifies novel regulators of synaptogenesis in a high-throughput RNAi screen of primary neurons. PLoS One. 2014;9(3):e91744. doi:10.1371/journal.pone.0091744

Activity-dependent p25 generation regulates synaptic plasticity and Aβ-induced cognitive impairment.

Seo J, Giusti-Rodríguez P, Zhou Y, et al. Activity-dependent p25 generation regulates synaptic plasticity and Aβ-induced cognitive impairment. Cell. 2014;157(2):486-98. doi:10.1016/j.cell.2014.01.065

Life extension factor klotho enhances cognition.

Dubal DB, Yokoyama JS, Zhu L, et al. Life extension factor klotho enhances cognition. Cell Rep. 2014;7(4):1065-76. doi:10.1016/j.celrep.2014.03.076

Synaptic, transcriptional and chromatin genes disrupted in autism.

De Rubeis S, He X, Goldberg AP, et al. Synaptic, transcriptional and chromatin genes disrupted in autism. Nature. 2014;515(7526):209-15. doi:10.1038/nature13772

p53 prevents neurodegeneration by regulating synaptic genes.

Merlo P, Frost B, Peng S, Yang YJ, Park PJ, Feany M. p53 prevents neurodegeneration by regulating synaptic genes. Proc Natl Acad Sci U S A. 2014;111(50):18055-60. doi:10.1073/pnas.1419083111

Genetic studies of body mass index yield new insights for obesity biology.

Locke AE, Kahali B, Berndt SI, et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015;518(7538):197-206. doi:10.1038/nature14177

Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy.

Dejanovic B, Djémié T, Grünewald N, et al. Simultaneous impairment of neuronal and metabolic function of mutated gephyrin in a patient with epileptic encephalopathy. EMBO Mol Med. 2015;7(12):1580-94. doi:10.15252/emmm.201505323