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Ribosomal protein mutations induce autophagy through S6 kinase inhibition of the insulin pathway.

Heijnen HF, van Wijk R, Pereboom TC, et al. Ribosomal protein mutations induce autophagy through S6 kinase inhibition of the insulin pathway. PLoS Genet. 2014;10(5):e1004371. doi:10.1371/journal.pgen.1004371

Ubiquitin-mediated response to microsporidia and virus infection in C. elegans.

Bakowski MA, Desjardins CA, Smelkinson MG, et al. Ubiquitin-mediated response to microsporidia and virus infection in C. elegans. PLoS Pathog. 2014;10(6):e1004200. doi:10.1371/journal.ppat.1004200

Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy.

Lan YY, Londoño D, Bouley R, Rooney MS, Hacohen N. Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy. Cell Rep. 2014;9(1):180-92. doi:10.1016/j.celrep.2014.08.074

Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer.

Buffen K, Oosting M, Quintin J, et al. Autophagy controls BCG-induced trained immunity and the response to intravesical BCG therapy for bladder cancer. PLoS Pathog. 2014;10(10):e1004485. doi:10.1371/journal.ppat.1004485

Nutrient-sensing mechanisms and pathways.

Efeyan A, Comb WC, Sabatini DM. Nutrient-sensing mechanisms and pathways. Nature. 2015;517(7534):302-10. doi:10.1038/nature14190

Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.

Di Nardo A, Wertz MH, Kwiatkowski E, et al. Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1. Hum Mol Genet. 2014;23(14):3865-74. doi:10.1093/hmg/ddu101