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      1. Carlos Slim Center for Health Research The Slim Center aims to bring the benefits of genomics-driven medicine to Latin America, gleaning new insights into diseases with relevance to the region.
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      5. Novo Nordisk Foundation Center for Genomic Mechanisms of Disease This center is developing new paradigms and technologies to scale the discovery of biological mechanisms of common, complex diseases, by facilitating close collaborations between the Ó³»­´«Ã½ and the Danish research community.
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      7. Stanley Center for Psychiatric Research The Stanley Center aims to reduce the burden of serious mental illness by contributing new insights into pathogenesis, identifying biomarkers, and paving the way toward new treatments.
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Post-transcriptional splicing can occur in a slow-moving zone around the gene.
Coté A, O’Farrell A, Dardani I, et al. Post-transcriptional splicing can occur in a slow-moving zone around the gene. eLife. 2024;12. doi:10.7554/eLife.91357
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DNA methylation-environment interactions in the human genome.
Johnston RA, Aracena KA, Barreiro LB, Lea AJ, Tung J. DNA methylation-environment interactions in the human genome. eLife. 2024;12. doi:10.7554/eLife.89371
Read more
Particulate matter from car exhaust alters function of human iPSC-derived microglia.
Jäntti H, Jonk S, Budia MG, et al. Particulate matter from car exhaust alters function of human iPSC-derived microglia. Particle and fibre toxicology. 2024;21(1):6. doi:10.1186/s12989-024-00564-y
Read more
Particulate matter from car exhaust alters function of human iPSC-derived microglia.
Jäntti H, Jonk S, Budia MG, et al. Particulate matter from car exhaust alters function of human iPSC-derived microglia. Particle and fibre toxicology. 2024;21(1):6. doi:10.1186/s12989-024-00564-y
Read more
A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells.
Antonova AU, Lonardi S, Monti M, et al. A distinct human cell type expressing MHCII and RORγt with dual characteristics of dendritic cells and type 3 innate lymphoid cells. Proceedings of the National Academy of Sciences of the United States of America. 2023;120(52):e2318710120. doi:10.1073/pnas.2318710120
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Modeling human immune responses to vaccination in vitro.
Morrocchi E, van Haren S, Palma P, Levy O. Modeling human immune responses to vaccination in vitro. Trends in immunology. 2024;45(1):32-47. doi:10.1016/j.it.2023.11.002
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Identifying metabolic features of colorectal cancer liability using Mendelian randomization.
Bull C, Hazelwood E, Bell JA, et al. Identifying metabolic features of colorectal cancer liability using Mendelian randomization. eLife. 2023;12. doi:10.7554/eLife.87894
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Learning functional conservation between human and pig to decipher evolutionary mechanisms underlying gene expression and complex traits.
Li J, Zhao T, Guan D, et al. Learning functional conservation between human and pig to decipher evolutionary mechanisms underlying gene expression and complex traits. Cell genomics. 2023;3(10):100390. doi:10.1016/j.xgen.2023.100390
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High-content microscopy reveals a morphological signature of bortezomib resistance.
Kelley ME, Berman AY, Stirling DR, et al. High-content microscopy reveals a morphological signature of bortezomib resistance. eLife. 2023;12. doi:10.7554/eLife.91362
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Fluorescein-based sensors to purify human a-cells for functional and transcriptomic analyses.
Kahraman S, Shibue K, De Jesus DF, et al. Fluorescein-based sensors to purify human a-cells for functional and transcriptomic analyses. eLife. 2023;12. doi:10.7554/eLife.85056
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In March of 2020, Ó³»­´«Ã½ converted a clinical genetics processing lab into a large-scale COVID-19 testing facility in less than two weeks.

We've screened more than 1,275 cancer cell lines as part of the Cancer Dependency Map (DepMap).

Ó³»­´«Ã½ Genomics Platform sequences a whole human genome every four minutes.

More than 11,000 individuals living with cancer in the United States and Canada have partnered with Count Me In to share their experiences and help accelerate cancer research.

The Drug Repurposing Hub is one of the most comprehensive and up-to-date biologically annotated collections of FDA-approved compounds in the world. Researchers anywhere can explore more than 6,000 drugs in the hub and search for possible new uses for them to jump-start new drug discovery.

In 2021, our sustainability efforts sent more than 80 percent of waste from the Genomics Platform to either a recycling facility or to an incineration plant that generates electricity.

Through Ó³»­´«Ã½'s Scientists in the Classroom program, Ó³»­´«Ã½ researchers visit every 8th grade classroom in Cambridge each year to talk about genetics and evolution.

Every summer, 18 high school students spend six weeks at Ó³»­´«Ã½ working side-by-side with mentors on cutting-edge research.

In November 2022, Ó³»­´«Ã½â€™s Genomics Platform sequenced its 500,000th whole human genome, a mere four years after sequencing its 100,000th.

By the end of 2022, Ó³»­´«Ã½â€™s COVID-19 testing lab had processed more than 37 million tests.

Working with Addgene, Ó³»­´«Ã½ has shared CRISPR genome-editing reagents with researchers at more than 3,200 institutions in 76 countries.

The NeuroGAP-Psychosis project, a collaboration between the Stanley Center for Psychiatric Research and Harvard T.H. Chan School of Public Health to study the genetics of severe mental illness, has recruited more than 42,000 participants in Ethiopia, Kenya, Uganda, and South Africa.

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