Nuttle X, Burt ND, Currall B, et al. Parallelized engineering of mutational models using piggyBac transposon delivery of CRISPR libraries. Cell reports methods. 2023:100672. doi:10.1016/j.crmeth.2023.100672
Li T, Ferraro N, Strober BJ, et al. The functional impact of rare variation across the regulatory cascade. Cell genomics. 2023;3(10):100401. doi:10.1016/j.xgen.2023.100401
Griffith AL, Zheng F, McGee A V, et al. Optimization of Cas12a for multiplexed genome-scale transcriptional activation. Cell genomics. 2023;3(9):100387. doi:10.1016/j.xgen.2023.100387
Krill-Burger M, Dempster JM, Borah AA, et al. Partial gene suppression improves identification of cancer vulnerabilities when CRISPR-Cas9 knockout is pan-lethal. Genome biology. 2023;24(1):192. doi:10.1186/s13059-023-03020-w
Benson MD, Eisman AS, Tahir UA, et al. Protein-metabolite association studies identify novel proteomic determinants of metabolite levels in human plasma. Cell metabolism. 2023. doi:10.1016/j.cmet.2023.07.012
Fowler DM, Adams DJ, Gloyn AL, et al. An Atlas of Variant Effects to understand the genome at nucleotide resolution. Genome biology. 2023;24(1):147. doi:10.1186/s13059-023-02986-x
Lue NZ, Liau BB. Base editor screens for in situ mutational scanning at scale. Molecular cell. 2023. doi:10.1016/j.molcel.2023.06.009
Myers SJ, Yuan H, Perszyk RE, et al. Classification of missense variants in the N-methyl-D-aspartate receptor GRIN gene family as gain- or loss-of-function. Human molecular genetics. 2023. doi:10.1093/hmg/ddad104
Einson J, Glinos D, Boerwinkle E, et al. Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants. Genetics. 2023. doi:10.1093/genetics/iyad115
Ngan KCH, Hoenig SM, Kwok HS, et al. Activity-based CRISPR scanning uncovers allostery in DNA methylation maintenance machinery. eLife. 2023;12. doi:10.7554/eLife.80640