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Daniel Graham is the senior director of functional genomics in the Infectious Disease and Microbiome Program at the Ó³»­´«Ã½ of MIT and Harvard, where he is also an institute scientist. leverages insights from human genetics to dissect molecular mechanisms of immunity and inflammatory pathologies. His work addresses how genetic and environmental factors, such as the microbiome, impact immune function in the context of health and autoimmune disease. The overarching goal of this work is to build towards a deep mechanistic understanding of disease pathophysiology and to inform new strategies for therapeutic intervention that can be tested with chemical biology approaches. By bridging diverse scientific disciplines through collaboration, these efforts aim to discover fundamental mechanisms of immunity and make direct connections with human biology.

Graham’s research collaborations span across the extended Ó³»­´«Ã½ community. He is a recipient of a Merkin Institute Fellowship at the Ó³»­´«Ã½, a member of the Center for the Study of Inflammatory Bowel Disease (CSIBD) at Massachusetts General Hospital and Harvard Medical School, and a member of the Center for Microbiome Informatics and Therapeutics (CMIT) at MIT. Prior to joining the Ó³»­´«Ã½, Graham completed a postdoctoral fellowship at Washington University School of Medicine in St. Louis in the Division of Immunobiology. He earned a Ph.D. in immunology from the Mayo Clinic College of Medicine and studied biochemistry at Bates College.