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Ó³»­´«Ã½ scientists are using brain, kidney, and tumor organoids to gain new insights into disease mechanisms and therapeutic approaches.

Findings offer a roadmap for how to build compounds to target proteins for degradation by the cell’s recycling system.

Cancer cells that have lost a copy of a critical gene may be vulnerable to therapies that knock out the remaining copy

Cas9 can cut DNA without any guide RNA and select for cells with inactivated p53.

Study reveals that ancestry-associated features are found in hundreds of genes, and are closely tied to specific tissues

Single-cell RNA sequencing maps immune microenvironment changes that arise before myeloma appears, and reveals opportunities for developing personalized treatments.

Study suggests chemotherapy itself can cause gliomas to mutate more, and that mutation burden alone is not enough to rouse the immune system against them.

Tests that look for hundreds of tumor mutations in blood samples could one day be used to detect residual disease in patients after treatment.

After living with angiosarcoma for decades, Jim Chapdelaine found support in an online community of patients and contributed to research that’s now shedding light on the roots of his own illness

Largest study yet of angiosarcoma reveals new mutations and suggests therapeutic possibilities for some subtypes