The fungus that causes athlete’s foot and other skin and toenail infections may have lost its ability to sexually reproduce as it adapted to grow on human hosts.
A strip of paper can now indicate presence of pathogens, tumor DNA, or any genetic signature of interest. 100-fold greater sensitivity, the ability to detect multiple targets at once, and other new features further enhance SHERLOCK's power for detecting genetic signatures.
Inspired by rare genetic disease, researchers develop a compound that can protect kidney cells from death and restore kidney function in multiple animal models of progressive kidney disease.
Following up on findings from genome-wide association studies, researchers identify two mechanisms by which disruptions in the gene SLC16A11 may play a role in type 2 diabetes
Single-cell analysis of human brain organoids cultured for more than nine months reveals novel neuron diversity, maturation, and responsiveness — suggesting potential use for modeling brain development and neuropsychiatric disease.
Ó³»´«Ã½ scientists deploy RNA sequencing to nail down disease-causing gene mutations in patients for whom genetic analysis failed to return a diagnosis. The study demonstrates the power of RNA sequencing to augment standard diagnostic tools in the clinic.
Using technologies previously developed at the Ó³»´«Ã½, researchers have analyzed nearly all genetic variants in the oncogene MAPK1/ERK2, revealing insights that could inform treatment.
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