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New research uses genetic and behavioral data to shed light on autism-associated traits in the general population

Synergy between two large cancer datasets may help identify a targetable weakness across many cancers

When making a simple telescope, relative adjustments between two lenses can bring previously blurry objects sharply into focus. Peering through two such “lenses” recently led to a discovery that may help identify which patients could most benefit from taking aim at a potentially widespread cancer therapeutic target.

Cancers can be cunning beasts and one of their favorite opportunities is something called a chromosomal translocation. Chromosomes are the 23 packages in every cell of condensed DNA. Translocations happen when the DNA breaks and the ends reattach elsewhere. DNA breakage actually occurs somewhat frequently, even in healthy individuals. But a series of ancient and very smart cellular processes ensure that things get put back in the right place — except when they don’t.

When Ebola Zaire swept across West Africa in early 2014, a research team led by ӳ����ý member Pardis Sabeti worked with collaborators from Sierra Leone and around the world to collect samples, rapidly sequence genomes, and share data in order to accelerate the outbreak response effort.