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Bacterial Genomics Group

Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance.

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Bronson RA, Gupta C, Manson AL, et al. Global phylogenomic analyses of Mycobacterium abscessus provide context for non cystic fibrosis infections and the evolution of antibiotic resistance. Nat Commun. 2021;12(1):5145. doi:10.1038/s41467-021-25484-9.

Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics.

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Ma P, He LL, Pironti A, et al. Genetic determinants facilitating the evolution of resistance to carbapenem antibiotics. Elife. 2021;10. doi:10.7554/eLife.67310.

Clinically relevant mutations in core metabolic genes confer antibiotic resistance.

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Lopatkin AJ, Bening SC, Manson AL, et al. Clinically relevant mutations in core metabolic genes confer antibiotic resistance. Science. 2021;371(6531). doi:10.1126/science.aba0862.

Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections.

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Straub TJ, Chou W-C, Manson AL, et al. Limited effects of long-term daily cranberry consumption on the gut microbiome in a placebo-controlled study of women with recurrent urinary tract infections. BMC Microbiol. 2021;21(1):53. doi:10.1186/s12866-021-02106-4.

Acquisition and Long-term Carriage of Multidrug-Resistant Organisms in US International Travelers.

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Worby CJ, Earl AM, Turbett SE, et al. Acquisition and Long-term Carriage of Multidrug-Resistant Organisms in US International Travelers. Open Forum Infect Dis. 2020;7(12):ofaa543. doi:10.1093/ofid/ofaa543.

Genes Contributing to the Unique Biology and Intrinsic Antibiotic Resistance of Enterococcus faecalis.

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Gilmore MS, Salamzade R, Selleck E, et al. Genes Contributing to the Unique Biology and Intrinsic Antibiotic Resistance of Enterococcus faecalis. mBio. 2020;11(6). doi:10.1128/mBio.02962-20.

Evidence for Expanding the Role of Streptomycin in the Management of Drug-Resistant Mycobacterium tuberculosis.

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Cohen KA, Stott KE, Munsamy V, Manson AL, Earl AM, Pym AS. Evidence for Expanding the Role of Streptomycin in the Management of Drug-Resistant Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2020;64(9). doi:10.1128/AAC.00860-20.

Spatially distinct physiology of Bacteroides fragilis within the proximal colon of gnotobiotic mice.

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Donaldson GP, Chou W-C, Manson AL, et al. Spatially distinct physiology of Bacteroides fragilis within the proximal colon of gnotobiotic mice. Nat Microbiol. 2020;5(5):746-756. doi:10.1038/s41564-020-0683-3.

Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae.

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Ernst CM, Braxton JR, Rodriguez-Osorio CA, et al. Adaptive evolution of virulence and persistence in carbapenem-resistant Klebsiella pneumoniae. Nat Med. 2020. doi:10.1038/s41591-020-0825-4.

Acquisition of Antibiotic-Resistant Bacteria by U.S. International Travelers.

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Mellon G, Turbett SE, Worby C, et al. Acquisition of Antibiotic-Resistant Bacteria by U.S. International Travelers. N Engl J Med. 2020;382(14):1372-1374. doi:10.1056/NEJMc1912464.