Finnish children carrying the high-risk HLA genotype have a 45-fold increased risk of type 1 diabetes compared to peers with neutral or protective genotypes.
Diabetes research and clinical practice
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Abstract | The association between HLA genotypes and type 1 diabetes is well known. We set out to examine incidence rates and ratios of type 1 diabetes depending on the risk afflicted by HLA genotype. Children with the high-risk genotype have a 45-fold disease risk compared to peers with neutral or protective genotypes. |
Year of Publication | 2023
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Journal | Diabetes research and clinical practice
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Volume | 197
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Pages | 110256
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Date Published | 03/2023
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ISSN | 1872-8227
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DOI | 10.1016/j.diabres.2023.110256
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PubMed ID | 36640866
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