ER Stress Promotes Inflammation through Re-wIREd Macrophages in Obesity.
Mol Cell
| Authors | |
| Keywords | |
| Abstract | A new mechanism linking ER dysfunction to metabolic inflammation is discovered in a recent study by Shan et al. (2017), which demonstrated ER stress-induced rewiring of adipose tissue macrophage polarization by IRE1α activation, leading to impaired systemic glucose homeostasis. |
| Year of Publication | 2017
|
| Journal | Mol Cell
|
| Volume | 66
|
| Issue | 6
|
| Pages | 731-733
|
| Date Published | 2017 Jun 15
|
| ISSN | 1097-4164
|
| DOI | 10.1016/j.molcel.2017.05.037
|
| PubMed ID | 28622517
|
| Links |