Fifth Annual Kidney-NExT Symposium: New Horizons for Kidney Therapeutics
This annual one-day symposium, chaired by institute member of the Ó³»´«Ã½ and faculty at Brigham and Women’s Hospital and Harvard Medical School, Dr. Anna Greka, will bring together leading stakeholders to discuss how we can advance the quest for novel therapeutics for kidney diseases, an area of tremendous unmet need. The Kidney-NExT Symposium is a unique forum for shared dialogue between academia and industry leaders, the FDA and patients from across the country to shape the future of kidney treatments.
Thursday April 4, 2019
Ó³»´«Ã½
415 Main St., Monadnock Room
Cambridge, MA
Symposium Program
9:00 am
Welcome
Todd Golub and Anna Greka
Keynote Lecture 1
Chair: Todd Golub
9:15 am – 10:00 am
Big data and health outcomes: challenges and opportunities
Robert Califf
Session 1
Toward therapies for kidney diseases
Chairs: Amy Shulman and Opeyemi Olabisi
10:00 am – 10:30 am
SGLT2 inhibitors for diabetic kidney disease
Jim List
10:30 am – 11:00 am
Tolvaptan for polycystic kidney disease
Vincente Torres
11:30 am – 11:30am
New perspectives on endpoints and clinical trial design
Lesley Inker
Panel Discussion and Brainstorming Session: How much progress have we made in kidney therapeutics? What can be done better?
Facilitator: Anna Greka
11:30 am – 12:30 pm
Panelists: Dave White, patient advocate / Nicole Jefferson, patient advocate / Kimberly Smith, FDA / Mera Tilley, Goldfinch Bio / Uptal Patel, Gilead / Melissa West, Kidney Health Initiative / Eugene Rhee, MGH / Samir Parikh, BIDMC
12:30 pm – 1:15 pm
Lunch
Session 2
Frontiers: genomics, organoids and systems biology in the kidney space
Chairs: Brian Pereira and Joseph Bonventre
1:15 pm – 1:45 pm
A systems biology approach to ciliopathies
Peter Jackson
1:45 pm – 2:15 pm
A glomerulus on a chip: current technology and future directions
Samira Musah
2:15 pm – 2:45 pm
Kidney organoids in drug development
Beno Freedman
2:45 pm – 3:15 pm
A newly completed GWAS of diabetic kidney disease
Joanne Cole
3:15 pm – 3:30 pm
Coffee break
Keynote Lecture 2
Chair: Krzystzof Kiryluk
3:30 pm – 4:15 pm
Predicting risk for common deadly diseases from millions of genetic variants
Sekar Kathiresan