Esther Uduehi
Society is beset by many untreatable or incurable diseases. Current drug discovery methods are not measuring up to the social demands for new and more effective treatments. The Ó³»´«Ã½ is committed to developing small-molecule probes to find new treatments for these incurable diseases -- and dedicated to making this information available to the public. The goal of Esther's research project this summer was to create skeletally diverse macrocycles -- molecules with a certain structure -- for a future small-molecule library design.
The preparation of small molecules libraries using diversity-oriented synthesis (DOS) is one approach for the discovery of biological probes and pharmaceutical agents that could illuminate pathways to potential new drug therapies.
PROJECT: Accessing Skeletal Diversity Using Catalytic Control: Synthesis of a Macrocyclic Triazole Library
I have learned so much from this summer research experience. Apart from different chemical techniques and mechanisms, I have been able to become a better scientist, overall. My mentor taught me how to balance science and other aspects of my life, which I find very important as I want to pursue graduate school.
