Denson LA, Jurickova I, Karns R, et al. Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients With Crohn’s Disease. Gastroenterology. 2018;154(8):2097-2110. doi:10.1053/j.gastro.2018.02.016
Baillie K, Bretherick A, Haley CS, et al. Shared activity patterns arising at genetic susceptibility loci reveal underlying genomic and cellular architecture of human disease. PLoS Comput Biol. 2018;14(3):e1005934. doi:10.1371/journal.pcbi.1005934
Chang YL, Rossetti M, Vlamakis H, et al. A screen of Crohn’s disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. Mucosal Immunol. 2019;12(2):457-467. doi:10.1038/s41385-018-0022-7
Nakata T, Creasey EA, Kadoki M, et al. A missense variant in confers risk for Crohn’s disease by disrupting manganese homeostasis and intestinal barrier integrity. Proc Natl Acad Sci U S A. 2020;117(46):28930-28938. doi:10.1073/pnas.2014742117
Rivas MA, Avila BE, Koskela J, et al. Insights into the genetic epidemiology of Crohn’s and rare diseases in the Ashkenazi Jewish population. PLoS Genet. 2018;14(5):e1007329. doi:10.1371/journal.pgen.1007329
Li D, Haritunians T, Landers C, et al. Late-Onset Crohn’s Disease Is A Subgroup Distinct in Genetic and Behavioral Risk Factors With UC-Like Characteristics. Inflamm Bowel Dis. 2018;24(11):2413-2422. doi:10.1093/ibd/izy148
Ananthakrishnan AN, Luo C, Yajnik V, et al. Gut Microbiome Function Predicts Response to Anti-integrin Biologic Therapy in Inflammatory Bowel Diseases. Cell Host Microbe. 2017;21(5):603-610.e3. doi:10.1016/j.chom.2017.04.010
Cross-Disorder Group of the Psychiatric Genomics Consortium, Lee H, Ripke S, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nat Genet. 2013;45(9):984-94. doi:10.1038/ng.2711
Khalili H, de Silva PS, Ananthakrishnan AN, et al. Dietary Iron and Heme Iron Consumption, Genetic Susceptibility, and Risk of Crohn’s Disease and Ulcerative Colitis. Inflamm Bowel Dis. 2017;23(7):1088-1095. doi:10.1097/MIB.0000000000001161
Huang H, Fang M, Jostins L, et al. Fine-mapping inflammatory bowel disease loci to single-variant resolution. Nature. 2017;547(7662):173-178. doi:10.1038/nature22969