Leshchiner ES, Rush JS, Durney MA, et al. Small-molecule inhibitors directly target CARD9 and mimic its protective variant in inflammatory bowel disease. Proc Natl Acad Sci U S A. 2017;114(43):11392-11397. doi:10.1073/pnas.1705748114
Hall AB, Tolonen AC, Xavier RJ. Human genetic variation and the gut microbiome in disease. Nat Rev Genet. 2017;18(11):690-699. doi:10.1038/nrg.2017.63
Niestroj LM, Du J, Nothnagel M, et al. Guideline-based and bioinformatic reassessment of lesion-associated gene and variant pathogenicity in focal human epilepsies. Epilepsia. 2018;59(11):2145-2152. doi:10.1111/epi.14579
Guo M, Liu Z, Willen J, et al. Epigenetic profiling of growth plate chondrocytes sheds insight into regulatory genetic variation influencing height. Elife. 2017;6. doi:10.7554/eLife.29329
Musunuru K, Bernstein D, Cole S, et al. Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research. Circ Genom Precis Med. 2018;11(4):e002178. doi:10.1161/CIRCGEN.118.002178
Raisner RM, Hartley PD, Meneghini MD, et al. Histone variant H2A.Z marks the 5’ ends of both active and inactive genes in euchromatin. Cell. 2005;123(2):233-48. doi:10.1016/j.cell.2005.10.002
Weiner DJ, Wigdor EM, Ripke S, et al. Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. Nat Genet. 2017;49(7):978-985. doi:10.1038/ng.3863
Nyegaard M, Severinsen JE, Als TD, et al. Support of association between BRD1 and both schizophrenia and bipolar affective disorder. Am J Med Genet B Neuropsychiatr Genet. 2010;153B(2):582-591. doi:10.1002/ajmg.b.31023
Lin WY, Chen WJ, Liu CM, et al. Adaptive combination of Bayes factors as a powerful method for the joint analysis of rare and common variants. Sci Rep. 2017;7(1):13858. doi:10.1038/s41598-017-13177-7
Zhang G, Feenstra B, Bacelis J, et al. Genetic Associations with Gestational Duration and Spontaneous Preterm Birth. N Engl J Med. 2017;377(12):1156-1167. doi:10.1056/NEJMoa1612665